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KMID : 0604519950210020094
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Journal of the Society of Cosmetic Scientists of Korea
1995 Volume.21 No. 2 p.94 ~ p.111
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A Study of the relationship between partition coefficients of oils and antimicrtobial effects
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Han Jong-Sub
Kim Jong-Il
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Abstract
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In this study, the relationship between partition coefficients(Kw) of oils and antimicrobial effects Ivas investigated. The antimicrobial activity of paraben has been known to be controlled by the concentration of the paraben in the aqueous phase. The concentration of paraben in the aqueous phase was measured by the UV/VIS spectrophotometer at the wavelength of 256nm. It was found that the hydrocarbon oils and silicone oils had the lowest Kw value(<1.0) among the tested oils. Also, the emulsions which were made of oils having low Kw values had a good antimicrobial effects. Thus, the cosmetic safety against microorganisms could be improved by using the oils which have low Kw values.
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